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Ar ImmunologyDual-function alarmins in the heart of inflammation and disease D Bertheloot and E Latzstage tumor growth or blood vessel clogging. Interestingly, pIL-1 expression was shown to be increased before epithelial cell necrosis in a hypoxia-induced factor (HIF)-1a- and HIF-2a-dependent manner.154 The release of IL-1 promotes chemokine secretion and neutrophil infiltration. Moreover, extrace
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Ple sclerosis.158?60 Thus, platelet-originating IL-1 would be an early signal playing a central role in the establishment of cerebrovascular inflammation and subsequently devastating brain injury. Notably, similar mechanisms are involved in the ischemic heart following myocardial infarction. Indeed, IL-1 release from necrotic myocytes was shown to trigger acute inflammation by activating surroundi
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Ple sclerosis.158?60 Thus, platelet-originating IL-1 would be an early signal playing a central role in the establishment of cerebrovascular inflammation and subsequently devastating brain injury. Notably, similar mechanisms are involved in the ischemic heart following myocardial infarction. Indeed, IL-1 release from necrotic myocytes was shown to trigger acute inflammation by activating surroundi
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O long days. Plant Cell 24: 463-481. Morozov, I.Y., Jones, M.G., Gould, P.d., Crome, v., Wilson, J.B., Hall, A.J., Rigden, d.J., and Caddick, M.X. (2012). mRNA 3' tagging is induced by nonsense-mediated decay and promotes ribosome dissociation. Mol. Cell. Biol. 32: 2585-2595. Muench, d.G., Zhang, C., and dahodwala, M. (2012). Control of cytoplasmic translation in plants. Wiley Int. Rev. RNA 3: 178
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Ts shoot meristematic function in Arabidopsis. BMC Plant Biol. 12: 160. Stuger, R., Ranostaj, S., Materna, T., and Forreiter, C. (1999). Messenger RNA-binding properties of nonpolysomal ribonucleoproteins from heat-stressed tomato cells. Plant Physiol. 120: 23-32. Stupina, v.A., Yuan, X., Meskauskas, A., dinman, J.d., and Simon, A.E. (2011). Ribosome binding to a 5' translational enhancer is alter
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Ds to rapamycin susceptibility. BMC Plant Biol. 7: 26. Sormani, R., delannoy, E., Lageix, S., Bitton, F., Lanet, E., Saezvasquez, J., deragon, J.M., Renou, J.P., and Robaglia, C. (2011b). Sublethal cadmium intoxication in Arabidopsis thaliana impacts translation at multiple levels. Plant Cell Physiol. 52: 436-447. Stadler, M., Artiles, K., Pak, J., and Fire, A. (2012). Contributions of mRNA abunda
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Sible dual regulatory circuits involving AtS6K1 in the regulation of plant cell cycle and growth. Mol. Cells 33: 487-496. Silva-Filho, M.C. (2003). One ticket for multiple destinations: dual targeting of proteins to distinct subcellular locations. Curr. Opin. Plant Biol. 6: 589-595.22 ofThe Arabidopsis BookSimon, A.E., and Miller, W.A. (2013). 3' Cap-Independent Translation Enhancers of Plant Viru
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